Environmental control of nucleophilic catalysis in water.
نویسندگان
چکیده
The nucleophilic catalysis by a pyridyl group in ester/phosphate ester hydrolysis was modulated by the microenvironmental hydrophobicity around the catalyst. The catalytic efficiency was enhanced thousands or tens of thousands of times and the activity was maintained well below the pKa of the pyridyl group.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 21 شماره
صفحات -
تاریخ انتشار 2014